RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
RASSF1-A
RNA ID
RNA Type
mRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
NA
Target
NA
Pathway
RAS SIGNALING PATHWAY
PubMed ID
Title
DNMT3A silencing RASSF1A promotes cardiac fibrosis through upregulation of ERK1/2
Year
2014
Function
DNAMT3A likely plays an essential role in rassf1a mediated upregulation of erk1/2 in rat cardiac fibrosis. DNMT3A and Rassf1a may serve as a new mechanism for cardiac fibrosis.